Personal Info

E-mail: david.harris(at)bioch.ox.ac.uk

Tel: 01865 275347

Web Link: http://www.bioch.ox.ac.uk/aspsite/research/brochure/Harris/

Special responsibilities:

Vice-Principal, Junior Proctor; Director of Teaching in the Biochemistry department in Oxford, responsible for design and organization of the Biochemistry course. Biochemical Society (UK) Education Committee.

Academic Background:

David Harris carried out his DPhil research at the University of Amsterdam, and returned to Oxford to take up the Weir Junior Research Fellow at University College. He then was appointed to a University lectureship at Leeds University, where he taught from 1979 to 1986. He returned to Oxford to take up the EP Abraham Cephalosporin Fellowship in Biochemistry at St Anne’s.

Teaching Interests:

Undergraduate:

• Enzymology and control of enzyme action
• Bioenergetics
• Metabolism and metabolic control mechanisms

Graduate:

• Research Techniques
• Graduate teacher training
• Enzymology

Research Interests:

David Harris started out in Biochemistry by studying the mechanism of energy conservation and ATP synthesis in mitochondria. Following from this, he has developed research interests in pathological defects in energy metabolism (particularly in the heart), molecular motors, metabolic control, control of sporulation in bacteria and even in the study of ancient diets.

Selected Publications:

David Harris, Bioenergetics at a Glance, 1995
David Harris, Light Spectroscopy,1998
G. Solaini and D.A. Harris, ‘Biochemical dysfunction in heart mitochondrial exposed to ischaemia and reperfusion’, Biochem. J. 390 (2005), 377-94
F. Di Pancrazio, I. Mavelli, M. Isola, G. Losano, P. Pagliaro, D.A. Harris and G. Lippe, ‘In vitro and in vivo studies of F OF 1 ATP synthase regulation by the inhibitor protein IF 1 in goat heart’, Biochim. Biophys. Acta 1659 (2004), 52-62
J. Clarkson, J.-C. Shu, D.A. Harris, I.D. Campbell and M.D. Yudkin, ‘Fluorescence and kinetic analysis of the SpoIAB phosphorylation reaction, a key regulator of sporulation in B. subtilis’, Biochemistry 43 (2004), 3120-28
B.T. Fuller, J.L. Fuller, N.E. Sage, D.A. Harris, T.C. O’Connell and R.E. Hedges, ‘Nitrogen balance and ? 15N: why you’re not what you eat during nutritional stress’, Rapid Comm. Mass Spectrom. 19 (2005), 2497-2506
B.T. Fuller, J.L. Fuller, D.A. Harris and R.E. Hedges, ‘Detection of breast feeding and weaning in modern human infants with carbon and nitrogen stable isotope ratios’, Amer. J. Phys. Anthropol. 129 (2006), 279-93