Personal Info

Academic Background:

Jon Dilworth was an undergraduate student at Jesus College, Oxford, and then in 1967 went to the University of Sussex for a DPhil with Professor J. Chatt at the Unit of Nitrogen Fixation. He stayed at Sussex until 1985 (DSc 1981) when he moved to take the Chair of Chemistry at the University of Essex. In 1997 he became Fellow and Tutor in Chemistry at St Anne's.

Research Interests:

Jon Dilworth’s research interests lie in the applications of inorganic complexes in biomedicine, catalysis and materials. The biomedical research is directed to the development of new imaging and therapeutic agents based on complexes of technetium, rhenium and copper radioisotopes. The copper-based programme synthesises new radioactive complexes for use in imaging hypoxia to improve treatments for cancer. The catalysis work is directed to making novel metal-based catalysts with sulphur co-ligands. The materials research aims to make new metal-sulphur complexes as precursors for binary sulphides with novel electronic properties and suitable for use as engine oil additives.

Selected Publications:

Sofia I. Pascu, Philip A. Waghorn, Timothy D. Conry, Bonita Lin, Helen M. Betts, Jonathan R. Dilworth, Robert B. Sim, Grant C. Churchill, Franklin I. Aigbirhio, John E. Warren, ‘Cellular confocal fluorescence studies and cytotoxic activity of new Zn(ii) bis(thiosemicarbazonato) complexes’, Dalton Transactions 16 (2008), 2107-10

Simon R. Bayly, Andrew R. Cowley, Jonathan R. Dilworth, Caroline V. Ward, ‘Ruthenium complexes with tridentate PNX (X = O, S) donor ligands’, Dalton Transactions 16 (2008), 2190-98

Paul D. Bonnitcha, Amy L. Vavere, Jason S. Lewis, Jonathan R. Dilworth, ‘In Vitro and In Vivo Evaluation of Bifunctional Bisthiosemicarbazone 64Cu-Complexes for the Positron Emission Tomography Imaging of Hypoxia’, Journal of Medicinal Chemistry, ACS ASAP. Publisher: American Chemical Society (Abstract)

Sofia I. Pascu, Philip A. Waghorn, Timothy D. Conry, Helen M. Betts, Jonathan R. Dilworth, Grant C. Churchill, Tzveta Pokrovska, Martin Christlieb, Franklin I. Aigbirhio, John E. Warren, ‘Designing Zn(II) and Cu(II) derivatives as probes for in vitro fluorescence imaging’, Dalton Transactions 43 (2007), 4988-97

Martin Christlieb, Harriet S.R. Struthers, Paul D. Bonnitcha, Andrew R. Cowley, Jonathan R. Dilworth, ‘The exocyclic functionalization of bis(thiosemicarbazonate) complexes of zinc and copper: the synthesis of monomeric and dimeric species’, Dalton Transactions 43 (2007), 5043-54 (Abstract)

Andrew R. Cowley, Jonathan R. Dilworth, Maria Salichou, ‘Syntheses and structures of pyrazolylmethane complexes of rhenium(III), (IV) and (V)’ Dalton Transactions 16 (2007), 1621-29 (Bibliographic Information)

Martin Christlieb, Andrew R. Cowley, Jonathan R. Dilworth, Paul S. Donnelly, Brett M. Paterson, Harriet S.R. Struthers, Jonathan M. White, ‘New bimetallic compounds based on the bis(thiosemicarbazonato) motif’, Dalton Transactions 3 (2007), 327-31

Jason P. Holland, Franklin I. Aigbirhio, Helen M. Betts, Paul D. Bonnitcha, Paul Burke, Martin Christlieb, Grant C. Churchill, Andrew R. Cowley, Jonathan R. Dilworth, Paul S. Donnelly, Jennifer C. Green, Josephine M. Peach, Sridhar R. Vasudevan, John E. Warren, ‘Functionalized Bis(thiosemicarbazonato) Complexes of Zinc and Copper: Synthetic Platforms Toward Site-Specific Radiopharmaceuticals’, Inorganic Chemistry 46(2) (2007), 465-85