Alexopoulou, Dr Zoi


Zoi Alexopoulou

Lecturer in Medical Sciences

Academic background

Dr Zoi Alexopoulou is a doctor in neurology and a neuroscientist. She studied at St. Anne’s College, University of Oxford for both for her medical degree and for her DPhil (PhD) in Clinical Neurosciences. She is a lecturer at St. Anne’s and a Clinical Director in MSD. Her expertise lies in the pathophysiology and new drug development in neurodegenerative diseases, including Parkinson’s and Alzheimer’s diseases. In MSD, she is responsible for translational drug development as well as for running global clinical trials in neurology, infectious diseases (eg. antiviral drugs) and other medical specialties. She is an associate fellow of the Higher Education Academy.


Undergraduate: Medicine and Biomedical Sciences

Graduate: Graduate-Entry Medicice (Neuroscience) and student supervision

Research interests

Pathophysiology and new drug development in neurodegenerative diseases

Recent Publications

“The deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease”

Zoi Alexopoulou , Johannes Lang , Rebecca Perrett , Myriam Elschami , Madeleine ED Hurry , Aron Szabo , Olaf Ansorge , Tudor Fulga , George K Tofaris 

PNAS vol. 113 no. 32, E4688-E4697, DOI 10.1073/pnas.1523597113, PMID 27444016


The endosomal pathway in Parkinson’s disease

Perrett RM, Alexopoulou Z, Tofaris GK.

Mol Cell Neurosci. 2015 May;66(Pt A):21-8. doi: 10.1016/j.mcn.2015.02.009 PMID:25701813

Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia

Hadley G, Beard D, Alexopoulou Z, Sutherland B, Buchan A

Neuroscience Letters 706 (2019) 223–230,

Artefactual Elevation of Plasma sCD40L by Residual Platelets in Patients with Coronary Artery Disease.

Lee R, Antonopoulos A, Alexopoulou Z, Margaritis M, Kharbanda R, Choudhury R, Antoniades C, Channon KM.

Int J Cardiol. 2013 Sep 30;168(2):1648-50. doi: 10.1016/j.ijcard.2013.03.019 PMID: 23578897

Time Trends In Pediatric Hospitalizations For Hepatitis A in Greece (1999 – 2013). Assessment of the Impact of Universal Infant Immunization in 2008 

Papaevangelou, Z. Alexopoulou, C. Hadjichristodoulou, G. Kourlamba, A. Katsoulis, K. Theodoridou, V. Spoulou, M. Theodoridou

Human Vaccines &Immunotherapeutics, Volume 12 Issue 7. 2016

Time trends in paediatric Herpes Zoster hospitalization rates following universal varicella immunization

Critselis, Elena; Theodoridou, Kalliopi; Alexopoulou, Zoi; Theodoridou, Maria; Papaevangelou, Vassiliki

Pediatrics International, 4 March 2016