Dr
Zoi Alexopoulou
Lecturer in Medical Sciences
Academic background
Dr Zoi Alexopoulou is a doctor in neurology and a neuroscientist. She studied at St. Anne’s College, University of Oxford for both for her medical degree and for her DPhil (PhD) in Clinical Neurosciences. She is a lecturer at St. Anne’s and a Clinical Director in MSD. Her expertise lies in the pathophysiology and new drug development in neurodegenerative diseases, including Parkinson’s and Alzheimer’s diseases. In MSD, she is responsible for translational drug development as well as for running global clinical trials in neurology, infectious diseases (eg. antiviral drugs) and other medical specialties. She is an associate fellow of the Higher Education Academy.
Teaching
Undergraduate: Medicine and Biomedical Sciences
Graduate: Graduate-Entry Medicice (Neuroscience) and student supervision
Research interests
Pathophysiology and new drug development in neurodegenerative diseases
Recent Publications
“The deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease”
Zoi Alexopoulou , Johannes Lang , Rebecca Perrett , Myriam Elschami , Madeleine ED Hurry , Aron Szabo , Olaf Ansorge , Tudor Fulga , George K Tofaris
PNAS vol. 113 no. 32, E4688-E4697, DOI 10.1073/pnas.1523597113, PMID 27444016
The endosomal pathway in Parkinson’s disease
Perrett RM, Alexopoulou Z, Tofaris GK.
Mol Cell Neurosci. 2015 May;66(Pt A):21-8. doi: 10.1016/j.mcn.2015.02.009 PMID:25701813
Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia
Hadley G, Beard D, Alexopoulou Z, Sutherland B, Buchan A
Neuroscience Letters 706 (2019) 223–230, https://doi.org/10.1016/j.neulet.2019.05.023
Artefactual Elevation of Plasma sCD40L by Residual Platelets in Patients with Coronary Artery Disease.
Lee R, Antonopoulos A, Alexopoulou Z, Margaritis M, Kharbanda R, Choudhury R, Antoniades C, Channon KM.
Int J Cardiol. 2013 Sep 30;168(2):1648-50. doi: 10.1016/j.ijcard.2013.03.019 PMID: 23578897
Time Trends In Pediatric Hospitalizations For Hepatitis A in Greece (1999 – 2013). Assessment of the Impact of Universal Infant Immunization in 2008
Papaevangelou, Z. Alexopoulou, C. Hadjichristodoulou, G. Kourlamba, A. Katsoulis, K. Theodoridou, V. Spoulou, M. Theodoridou
Human Vaccines &Immunotherapeutics, Volume 12 Issue 7. 2016
Time trends in paediatric Herpes Zoster hospitalization rates following universal varicella immunization
Critselis, Elena; Theodoridou, Kalliopi; Alexopoulou, Zoi; Theodoridou, Maria; Papaevangelou, Vassiliki
Pediatrics International, 4 March 2016