Maclean, Patrick

Academic background

I trained as a junior doctor in Melbourne, Australia, and am now in my third year of DPhil here in Oxford. I am working on the epigenetic regulation of the host response to infectious diseases in the lab of Julian Knight at the Wellcome Trust Centre for Human Genetics.

Teaching

Undergraduate: Tutorials for 2^nd year medical students (Immunology and Infection)

Research interests

Short-lived infections can produce long-lasting alterations in the functional capacity of the immune system. I’m interested in understanding how the epigenetic profile of immune cells changes in response to severe infections, and whether these epigenetic ‘scars’ could be repaired using immune therapy.