Vyas, Professor Paresh


Paresh Vyas

Professorial Fellow in Medical Sciences
Professor of Haematology, Weatherall Institute of Molecular Medicine
Consultant Haematologist
Group Leader MRC Molecular Haematology Unit


Academic background

Paresh Vyas is Professor of Haematology at the University of Oxford. He studied medicine at Cambridge then Oxford. After completing his medical and haematology training in London, he did his PhD with Professor Doug Higgs and Professor Sir David Weatherall at the MRC Molecular Haematology Unit, Oxford. A three-year post-doctoral fellowship with Professor Stuart Orkin at Harvard University followed. He is a research-active Consultant Haematologist with a clinical practice in myeloid disorders: myelodysplastic syndrome, MDS, acute myeloid leukaemia, AML, and myeloproliferative disorders, MPD, as well as allogeneic stem cell transplant.


His research in the MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, focuses on molecular and cellular biology of AML and MDS with specific interest in purification and therapeutic targeting of myeloid stem cells. He studies single cell biology in normal and leukaemic haemopoiesis. He is on the UK AML and MDS clinical trial groups. He is co-Lead of the Oxford BRC Haematology and Stem Cells Theme, is on the Board of NHSBT, vice-chair of the MRC Clinical Training Panel and Translational Lead for the UK Therapy Acceleration Program.

Selected publications

Quek, L., David, M.D., Kennedy, A. et al. Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib. Nat Med 24, 1167–1177 (2018). https://doi.org/10.1038/s41591-018-0115-6

Karamitros, D., Stoilova, B., Aboukhalil, Z. et al. Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells. Nat Immunol 19, 85–97 (2018). https://doi.org/10.1038/s41590-017-0001-2